Van de Ven Double Halts Everton's Run at New Home Ground
The Dutch defender emerged as the initial backline player to net two goals in a Premier League match for Tottenham since Jan Vertonghen in spring 2013.
Key points
The Spurs defender nods into the net two times in opening period
The home side's Jake O'Brien has goal ruled after VAR review
Pape Matar Sarr nets third in 89th minute
This loss is the Merseyside club's initial at their new ground
Micky van de Ven found the net twice as Tottenham extended their winning streak on the road in the Premier League and delivered the Toffees their initial loss at their new home.
Everton were undefeated in their five previous fixtures at their new ground at Bramley-Moore Dock, having departed Goodison Park behind after more than a century at the end of the previous campaign.
But Tottenham's leader Van de Ven pounced on two occasions from corners in the first half to put their impressive record at risk, and they were failed to mount a comeback before Pape Matar Sarr - assisted by ex-Everton forward Richarlison - nodded in a third to seal the victory.
The Everton defender thought he had equalized the scores five minutes after the defender's first goal, glancing a bullet header past the Spurs keeper from an Everton corner.
Beto, in the meantime, failed to convert a handful of opportunities, while the Italian goalkeeper made a series of fine stops to ensure the London club went five matches on the road without defeat in the English top flight.
But the video assistant referee stepped in, advising the match official to review the score on the screen and the referee ruled that the winger and Iliman Ndiaye were in an illegal position and had interfered with the Spurs keeper.
This victory elevates Thomas Frank's team into third place in the Premier League, five points off north London rivals and leaders the Gunners.
The Merseyside club remain in 14th position and sit half a dozen points ahead of the relegation zone.
Spurs breakdown: The defender fulfils role at both ends of the field
Following a drab weekday performance in the Champions League against the French side, where they managed a mere attempts on goal, the manager opted for the French striker in attack instead of ex-Everton forward Richarlison.
The summer signing was unable to make much of an impact before being replaced for the substitute after an hour on the field, but it emerged he wasn't needed in the final outcome.
Centre-back the Dutchman transformed into an offensive threat to be reckoned with.
Spurs' first goal came from a well-worked corner routine, with the midfielder heading the ball toward the face of goal for an unmarked the defender to score.
And Ven de Ven - stepping up as skipper in the Argentine's unavailability - notched his next goal in first-half stoppage time as he rose above the England keeper to head home.
The Dutchman was equally impressive in defence, partnering effectively with Kevin Danso as the pair dealt excellently with the 34 crosses sent their way by the opposition.
Toffees breakdown: Toffees lacking striker's instinct
Everton's recent stadium had been a happy hunting ground, but it appears the freshness may have faded somewhat and fans flocked to the exits after Sarr's final goal for Tottenham.
The end in Everton's winning streak at home won't be a major concern for David Moyes, but their striker situation are.
Beto and the other striker - the Toffees' two recognised centre-forwards - had netted just one league goal between them before the weekend's match.
And they were unable to add to that miserable tally on a wet and gloomy night on Merseyside.
Beto's form was summed up when he opted to bicycle-kick a clear chance from close range, even with having room and opportunity to reposition for a simpler shot that would have challenged Vicario.
The substitute, as well, was unable to influence the game after replacing Beto in the second half.
It was not for a shortage of chance. The majority of Everton's attacks came through Grealish and Ndiaye, who relentlessly delivered dangerous balls into the Tottenham box.
What next for these two sides?
The Toffees: Moyes' men travel to the Stadium of Light in the Premier League on early November at 20:00 GMT.
Spurs: Spurs go to Newcastle's ground on late October for their next round Carabao Cup tie against the Magpies.